National Research Council of Italy

Institute of Biosciences and BioResources

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IBBR Project #321

EV-C@p: Plant-derived Extracellular Vesicles as novel biotechnological platform for biopharma applications (Progetti Grande Rilevanza 2023)
Project ID 321
ID KR23GR03
Acronym EV-C@p
Project acronym and title EV-C@p: Plant-derived Extracellular Vesicles as novel biotechnological platform for biopharma applications (Progetti Grande Rilevanza 2023)
Contract PGR10137
Description Going beyond the state-of-the-art and relying on highly interconnected approaches mastered by the applicants, in EV-C@p will setup a novel vegetable-based system for the production of nanovesicles and exploit them as a biotechnological platform for biopharma applications. This will be achieved through the isolation of EVs from organically grown tomato and panax ginseng and by the establishment of their in vitro cell cultures to biomanifacture EVs. By applying emerging biotechnology we will develop engineered EV-based solutions to create next generation nano-delivery systems. The native and the engineered plant EVs will be exploited for their health promoting anticancer and anti-inflammatory activities in vitro. To achieve the above objectives the EV-C@p consortium was created with the participation of two research groups (KHU and CNR) and two SMEs partners, ImmunoVeg from Italy and NIOBiopharmaceuticals from Korea. The project will strengthen the already existing collaborations between the two PIs and create new ones with the SMEs to provide a solid cornerstone for further research efforts of the participants and to make a prompt translation of the research results into new technology and products after the ending of the project. An ambitious staff exchange programme for the transfer of scientific and transferable skills, dissemination and outreach activities were implemented into the scientific plan.
Funding body Ministero degli Affari Esteri e della Cooperazione Internazionale (MAECI)
UOS Napoli
Role Coordinatore
Signatory Pocsfalvi Gabriella
Contact Person Pocsfalvi Gabriella
Starting of activities 2023
Ending of activities 2026
Extension -
Amount (euro) 180000.00
Technological Area -
Technological Field Nuove frontiere dell’alimentazione
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Istituto di Bioscienze e Biorisorse (IBBR/CNR)
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