Institute of Biosciences and Bioresources

National Research Council of Italy

Rosa Merlo

Role: PhD Student
Section: Guests
Division: Naples
Tel: (39) 081-6132496
E-mail: rosa.merlo@ibbr.cnr.it

Currently I am PhD student at the University of Naples “Federico II” and I work with Dr Giuseppe Perugino at the Institute of Biosciences and Bioresources (IBBR - UOS Naples).

Education and Training

2018-present: PhD in Biology (last year), University of Naples “Federico II”, Naples (Italy)

2016: Master degree in Medical Biotechnologies, LM-9-“MAGISTRALE” DEGREE CLASS IN MEDICAL, PHARMACEUTICAL AND VETERINARY BIOTECHNOLOGIES University of Naples "Federico II", Naples (Italy) with summa cum laude


  • Farag N., Mattossovich R., Merlo R., Nierzwicki Ł., Palermo G., Porchetta A., Perugino G., Ricci F. Folding-upon-repair DNA nanoswitches for monitoring DNA repair enzymes activity. Angew Chem Int Ed Engl. 2021 Jan 8. doi:10.1002/anie.202016223. Epub ahead of print. PMID:33415794.

  • Merlo R., Caprioglio D., Cillo M., Valenti A., Mattossovich R., Morrone C., Massarotti A., Rossi F., Miggiano R., Leonardi A., Minassi A., Perugino G. The SNAP- tag technology revised: an effective chemo-enzymatic approach by using a universal azide-based substrate J Enzyme Inhib Med Chem. 2021, 36(1):85-97. - doi: 10.1080/14756366.2020.1841182.
  • Mattossovich R.*, Merlo R.*, Miggiano R., Valenti A., Perugino G. O6-alkylguanine-DNA Alkyltransferases in Microbes Living on the Edge: From Stability to Applicability. Int. J. Mol. Sci. 2020, 21(8), 2878. doi.org/10.3390/ijms21082878.
  • Mattossovich R.*, Merlo R.*, Fontana A., d’Ippolito G., Terns M.P., Watts E.A., Valenti A., Perugino G. A journey down to hell: new thermostable protein-tags for biotechnology at high temperatures. Extremophiles 2020, 24(1):81-91. doi:10.1007/s00792-019-01134-3.
  • Del Prete S.*, Merlo R.*, Valenti A., Mattossovich R., Rossi M., Carginale V., Supuran C.T., Perugino G., Capasso C. Thermostability enhancement of the α-carbonic anhydrase from Sulfurihydrogenibium yellowstonense by using the anchoring-and-self-labelling-protein-tag system (ASLtag). J Enzyme Inhib Med Chem. 2019;34(1):946-954. doi:10.1080/14756366.2019.1605991.
  • Merlo R., Del Prete S., Valenti A., Mattossovich R., Carginale V., Supuran C.T., Capasso C., Perugino G. An AGT-based protein-tag system for the labelling and surface immobilization of enzymes on E. coli outer membrane. J Enzyme Inhib Med Chem. 2019;34(1):490-499. doi:10.1080/14756366.2018.1559161.

*These authors contributed equally


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