RNAi applications to control insect pests of agronomic and veterinary importance

Salvatore Arpaia 
ENEA, Italian National Agency for New Technologies, Energy and Sustainable Economic Development - Italy

November 20, 2024 (11:30-12:30)
Webinar Link: https://teams.microsoft.com/l/meetup-join/19:meeting_YTVlMjdlMGEtNTJhMi00M2E5LThhMzUtMDhkMjU2OGViOTUz@thread.v2/0?context={"Tid":"34c64e9f-d27f-4edd-a1f0-1397f0c84f94","Oid":"3bd84f77-18e6-4873-abd2-0f9c95cea55a"}

Abstract: RNA interference (RNAi) is a natural defense mechanism that eukaryotic organisms use to detect and neutralize foreign genetic material, particularly viral RNA. The discovery that double-stranded RNA molecules from external sources can trigger RNAi has sparked significant interest in both academic and industrial fields. This has led to various applications, such as genetically modified crops and insecticidal compounds. Initiatives like the UN Decade on Ecosystem Restoration and the European Green Deal aim to promote sustainable food production and reduce the use of synthetic pesticides. Due to its specific mode of action, RNAi can become an important resource for these policy goals. An important milestone came in December 2023, when the US-EPA approved the first sprayable dsRNA-based insecticide, marking a step forward for the technology. Although studies indicate limited risks for mammals and vertebrates, a safety evaluation is necessary to assess potential effects on human health and the environment

Author's Info: https://orcid.org/0000-0003-0455-3043